4.8 Article

Insights into the mechanism of the Negishi reaction:: ZnRX versus ZnR2 reagents

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 12, Pages 3508-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja070235b

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The observation that their transmetalations with trans-[PdRfCl(PPh3)(2)] (Rf = fluoroaryl) give stereoselectively a different isomer of [PdRfMe(PPh3)(2)] suggests that Negishi reactions with ZnRX or ZnR2 could show very different evolutions.

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