4.8 Article

Development of a library of 6-arylcoumarins as candidate fluorescent sensors

Journal

ORGANIC LETTERS
Volume 9, Issue 7, Pages 1315-1318

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol070142z

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A bromocoumarin scaffold (1) was reacted with various boronic acid derivatives (2a-l) to afford a library of 6-arylcoumarins (3a-l). This library was found to contain candidate fluorescent sensors for peptidase activity and for nitric oxide.

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