4.8 Article

Highly stereoselective [4+3] cycloadditions of nitrogen-stabilized oxyallyl cations with pyrroles. An approach to parvineostemonine

Journal

ORGANIC LETTERS
Volume 9, Issue 7, Pages 1275-1278

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol070103n

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Funding

  1. NIGMS NIH HHS [GM066055] Funding Source: Medline

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A highly stereoselective [4 + 3] cycloaddition of N-substituted pyrroles with allenamide-derived nitrogen-stabilized chiral oxyallyl cations is described here. This method provides an approach for constructing tropinone alkaloids.

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