Trifluoromethylation of alkenyl bromides and iodides (including 5-iodouracils) with (CF3)2Hg and Cu (trifluoromethylcopper)

[GRAPHIC] Bromo- and iodoalkenes undergo trifluoromethylation efficiently in DMA with CF3Cu generated from (CF3)(2)Hg and Cu. Variable stereochemical inversion is observed with substrates having a gem-carbonyl group. Substrates having gem-hydrogen, -alkyl, or -alkenyl groups give products with stereochemical retention.