☆ 4.8 Article

Elucidation of the alpha-Keto-Aldehyde Binding Mechanism: A Lead Structure Motif for Proteasome Inhibition

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

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Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 50, Issue 2, Pages 542-544

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201005488

Keywords

drug discovery; peptidyl glyoxals; proteasomes; reversible inhibition; structure elucidation

Categories

Chemistry, Multidisciplinary

Funding

  1. Peter und Traudl Engelhorn-Stiftung
  2. Deutsche Forschungsgemeinschaft [SFB595/TP A11]

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