Journal
JOURNAL OF ANTIBIOTICS
Volume 60, Issue 4, Pages 277-284Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ja.2007.35
Keywords
aminophenoxazinones; antitumor activity; Streptomyces; taxonomy; structure elucidation
Ask authors/readers for more resources
Two new aminophenoxazinone compounds with antitumor activity, elloxazinone A and B, were isolated from the culture filtrate of Streptomyces griseus Acta 2871. Their chemical structures were determined by mass spectrometry, NMR spectroscopy and X-ray analysis. Elloxazinones A and B showed a moderate inhibition of the proliferation of human cells from gastric adenocarcinoma in vitro but a strong inhibition of hepatocellular carcinoma cells whereas elloxazinone B strongly inhibited the proliferation of human breast carcinoma cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available