4.8 Article

5-(Pyrrolidin-2-yl)tetrazole-Catalyzed Aldol and Mannich Reactions: Acceleration and Lower Catalyst Loading in a Continuous-Flow Reactor

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 48, Issue 15, Pages 2699-2702

Publisher

WILEY-BLACKWELL
DOI: 10.1002/anie.200804407

Keywords

aldol reaction; asymmetric catalysis; continuous-flow reactors; microreactors; organocatalysis

Funding

  1. Swiss Federal Institute of Technology (ETH) Zurich
  2. Merck Sharp and Dohme

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