Journal
INFECTION AND IMMUNITY
Volume 75, Issue 4, Pages 2063-2066Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.01565-06
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Group B streptococcus (GBS) expresses a hemolysin/cytolysin that plays an important role in pathogenesis. Using the Himar1 transposon mutagenesis system, a hypohemolytic mutant carrying an interrupted cylJ gene was characterized. cylJ, encoding a putative glycosyltransferase, and cylK, whose product is unknown, are both required for the full hemolytic/cytolytic activity, pigment formation, and virulence of GBS.
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