Journal
PLANTA MEDICA
Volume 73, Issue 4, Pages 366-371Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-967131
Keywords
Spicellum roseum; marine-derived fungi; endophyte; Ectyplasia perox; depsipeptide
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Investigation of the secondary metabolites of the marine-derived fungus Spicellum roseum yielded two new cyclohexadepsipeptides, spicellamide A (1) and spicellamide B (2). The structures of 1 and 2 were determined based on extensive evaluations of NMR and MS data. The absolute configuration was deduced after hydrolysis using Marfey's method, chiral chromatography, as well as NOESY and modeling data.
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