☆ 4.8 Article

Molecular Recognition at the Active Site of Catechol-O-Methyltransferase: Energetically Favorable Replacement of a Water Molecule Imported by a Bisubstrate Inhibitor

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

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Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 48, Issue 48, Pages 9092-9096

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.200904410

Keywords

drug discovery; enzymes; inhibitors; medicinal chemistry; structure-activity relationships

Categories

Chemistry, Multidisciplinary

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