4.8 Article

Drug-loaded superparamagnetic iron oxide nanoparticles for combined cancer imaging and therapy in vivo

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 47, Issue 29, Pages 5362-5365

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.200800857

Keywords

antitumor agents; drug delivery; imaging agents; nanotechnology

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Multitasking rust ball: The questions of where a tumor is located, whether drugs are properly delivered to the tumor, and what the therapeutic response of the tumor is, could be answered by using simple but smart, drug-loaded superparamagnetic iron oxide nanoparticles that can accumulate in tumor with high efficiency thanks to the presence of rationally engineered polymer coating layers.

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