Journal
SCIENCE
Volume 316, Issue 5821, Pages 76-82Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1135935
Keywords
-
Categories
Funding
- Medical Research Council [G9200370] Funding Source: Medline
- Medical Research Council [G9200370] Funding Source: researchfish
- MRC [G9200370] Funding Source: UKRI
Ask authors/readers for more resources
Memory encoding occurs rapidly, but the consolidation of memory in the neocortex has long been held to be a more gradual process. We now report, however, that systems consolidation can occur extremely quickly if an associative schema into which new information is incorporated has previously been created. In experiments using a hippocampal-dependent paired-associate task for rats, the memory of flavor-place associations became persistent over time as a putative neocortical schema gradually developed. New traces, trained for only one trial, then became assimilated and rapidly hippocampal-independent. Schemas also played a causal role in the creation of lasting associative memory representations during one-trial learning. The concept of neocortical schemas may unite psychological accounts of knowledge structures with neurobiological theories of systems memory consolidation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available