4.8 Article

1,2-Sulfanyl group migration as a driving force: New approach to pyrroles by reaction of allenic aldehydes with amines

Journal

ORGANIC LETTERS
Volume 9, Issue 8, Pages 1445-1448

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol070205d

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Acid-promoted reaction of sulfanyl group substituted allenic aldehyde with amine affords pyrrole derivatives in high yields. The neighboring group participation of the sulfanyl group is the driving force in this transformation.

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