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Interpretation of microarray data in cancer

Journal

BRITISH JOURNAL OF CANCER
Volume 96, Issue 8, Pages 1155-1158

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6603673

Keywords

microarray; validation; prognostic; predictive

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Microarray studies aim at identifying homogeneous subtypes of cancer patients, searching for differentially expressed genes in tumours with different characteristics, or predicting the prognosis of patients. Using breast cancer as an example, we discuss the hypotheses underlying these studies, their power, and the validity and the clinical usefulness of the findings.

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