4.8 Article

Asymmetric hydrogenation of aryl ketones mediated by a copper catalyst

Journal

ORGANIC LETTERS
Volume 9, Issue 9, Pages 1655-1657

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol070289q

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A novel asymmetric hydrogenation protocol using a copper catalyst is reported. A Cu(I) complex in the presence of nonracemic BDPP hydrogenates aryl ketones with moderate to high enantioselectivity.

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