Journal
TETRAHEDRON-ASYMMETRY
Volume 18, Issue 7, Pages 852-856Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2007.03.022
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We report an asymmetric synthesis of the alkaloid fagomine, which is an inhibitor of mammalian alpha-glucosidase and beta-galactosidase, by means of Sharpless asymmetric dihydroxylation and Pd(II)-catalyzed cyclization, starting from 3-(t-butoxylcarbonylamino)propanol. (c) 2007 Elsevier Ltd. All rights reserved.
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