Journal
JOURNAL OF HEALTH PSYCHOLOGY
Volume 12, Issue 3, Pages 417-430Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1359105307076230
Keywords
assessment; cerebral malaria; Kenya; prophylaxis; seizures
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Funding
- NIMH NIH HHS [R21 MH72597-02] Funding Source: Medline
- Wellcome Trust [070114, 064702] Funding Source: Medline
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The purpose of the study was to develop a culture-informed measure of developmental outcome and to apply it to detect differences in developmental level between children with cerebral malaria enrolled in a clinical trial to control seizures during the acute phase of the illness. The instrument was administered to a sample of 180 children, three and 12 months after discharge from hospital. The measure demonstrated high internal consistency, good inter-observer reliability, age sensitivity and strong relations with parental report of child functioning. No association was found between performance, or change in performance, with the prophylactic regime administered. The results suggested that the use of Phenobarbital in controlling provoked seizures has no observable effect on cognitive function.
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