Journal
PHYTOTHERAPY RESEARCH
Volume 21, Issue 5, Pages 427-433Publisher
WILEY
DOI: 10.1002/ptr.2077
Keywords
Citrus medica L. cv. Diamante; Rutaccae; antioxidant and hypoglycaemic activities; Alzheimer's disease
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The present study showed for the first time the in vitro properties (antioxidant, hypoglycaemic and anticholinesterase) of Citrus medica L. cv. Diamante which belongs to the Rutaceae family. The n-hexane extract of Diamante citron peel is characterized by the presence of monoterpones and sesquiterpenes. The most abundant constituents were two monoterpenes limonene and gamma-terpinene. The extract showed significant antioxidant activity that was carried out using different assays (DPPH lest, beta-carotene bleaching test and bovine brain peroxidation assay). Oxidative damage, caused by the action of free radicals, may initiate and promote the progression of a number of chronic diseases, including diabetes and Alzheimer's disease. Diamante citron peel extract showed hypoglycaemic activity and an anticholinesterase effect. Copyright (c) 2007 John Wiley & Sons, Ltd.
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