Journal
GREEN CHEMISTRY
Volume 9, Issue 5, Pages 438-440Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b700923b
Keywords
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Funding
- Engineering and Physical Sciences Research Council [EP/C523970/1, EP/C523970/2] Funding Source: researchfish
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The combination of pot, atom and step economy (PASE) in the synthesis of organic molecules of medium complexity can lead to a significant 'greening' of a synthetic route. This is demonstrated by the synthesis of highly substituted tetrahydropyran-4-ones and is quantified by a series of recognised metrics, which demonstrate the efficiency of combining PASE over conventional synthetic strategies.
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