4.7 Article

Iron-catalysed sp3-sp3 cross-coupling reactions of unactivated alkyl halides with alkyl Grignard reagents

Journal

ADVANCED SYNTHESIS & CATALYSIS
Volume 349, Issue 7, Pages 1015-1018

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.200600383

Keywords

alkyl halides; cross-coupling; Grignard reactions; iron

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Iron-catalysed sp(3)-sp(3) Kumada coupling with primary and secondary alkyl halides (RX) and alkyl Grignard reagents has been achieved in low to good yields depending on the nature of the R group.

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