Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 73, Issue 9, Pages 3084-3090Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02893-06
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Funding
- Biotechnology and Biological Sciences Research Council [BBS/E/I/00000715] Funding Source: Medline
- Biotechnology and Biological Sciences Research Council [BBS/E/I/00000715] Funding Source: researchfish
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We used bovine intestinal organ culture to study infection by enterohemorrhagic Escherichia coli serogroups O157, O26, and O111. We show colonization and attaching and effacing lesion formation on explants derived from the ileum, colon, and rectum. Intimin and Tir were detected at the sites of adherent bacteria; Tir was essential for colonization.
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