Journal
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
Volume 133, Issue 5, Pages 471-476Publisher
AMER MEDICAL ASSOC
DOI: 10.1001/archotol.133.5.471
Keywords
-
Categories
Funding
- PHS HHS [R01-106908] Funding Source: Medline
Ask authors/readers for more resources
Objective: To determine whether a self-reported, subjective general health assessment tool can provide prognostic information about survival in patients with head and neck cancer. Design: Prospective observational cohort study. Setting: Tertiary care center. Patients: Five hundred seventy-one patients with squamous cell carcinoma of the upper aerodigestive tract who were enrolled in the institution's longitudinal Outcomes Assessment Project between January 1, 1995, and November 30, 2004. Main Outcome Measures: Actuarial 5-year observed and disease-specific survival. Results: The physical component summary obtained from the SF-36 (Medical Outcomes Study 36-Item Short-Form Health Survey) was significantly associated with ACE-27 (Adult Comorbidity Evaluation-27) comorbidity ratings. The mental component summary was not associated with ACE-27 scores or survival. Although the comorbidity rating was an independent predictor of observed survival (P = .002) only, the physical component summary was independently predictive of both observed (P < .001) and disease-specific (P = .001) survival. These associations continued to be independently significant when site and stage were included in the analysis (P = .003, P < .001, and P = .004, respectively). Conclusion: The physical component summary generated by the SF-36, a self-reported, subjective measure of general physical health, is predictive of both observed and disease-specific survival.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available