Journal
LETTERS IN APPLIED MICROBIOLOGY
Volume 44, Issue 5, Pages 459-466Publisher
WILEY
DOI: 10.1111/j.1472-765X.2007.02130.x
Keywords
cystic fibrosis CF; mycobacteria other than tubercle bacilli; Mycobacterium abscessus; nontuberculous mycobacteria; PCR; tuberculosis
Categories
Ask authors/readers for more resources
While patients with cystic fibrosis (CF) have had dramatic improvement in their survival rates, this has been accompanied by the emergence of more virulent pathogens such as Pseudomonas aeruginosa and Burkholderia cepacia complex organisms. In addition, there has been emergence of organisms of increasing clinical significance such as the nontuberculous mycobacterial (NTM). Although TB infection in patients with CF is extremely uncommon, there is growing concern with regard to atypical Mycobacterium spp, in particular Mycobacterium abscessus. Many methods of decontamination of sputum, which have been adapted from TB methodologies, are ineffective; as shown by the overgrowth of P. aeruginosa, it is essential that decontamination methods are optimized to overcome this. Establishing optimal methods of isolation and determining accurate levels of prevalence is of importance as, although NTM may be isolated relatively infrequently in CF populations, their clinical status in pulmonary disease is now beginning to emerge.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available