Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 51, Issue 5, Pages 1835-1836Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01534-06
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Funding
- NIAID NIH HHS [N01 AI00042] Funding Source: Medline
- Wellcome Trust [077166/Z/05/Z] Funding Source: Medline
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Ex vivo conversion of the anti-influenza drug oseltamivir to its active metabolite can be inhibited by the esterase inhibitor dichlorvos or by using commercial fluoride-oxalate tubes. Oseltamivir and its active metabolite remain intact in plasma samples during a proposed virus heat inactivation step: incubation at 60 degrees C for 45 min.
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