4.6 Article

Reversal of rocuronium-induced (1.2 mg kg-1) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg-1)

Journal

BRITISH JOURNAL OF ANAESTHESIA
Volume 98, Issue 5, Pages 624-627

Publisher

ELSEVIER SCI LTD
DOI: 10.1093/bja/aem057

Keywords

neuromuscular block, rocuronium; neuromuscular relaxant, sugammadex; reversal agent

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Sugammadex is the first selective relaxant binding agent and reverses rocuronium-induced neuromuscular block. A case is reported in which a patient accidentally received a high dose of sugammadex (40 mg kg(-1)) to reverse a rocuronium-induced (1.2 mg kg(-1)) profound neuromuscular block. A fast and efficient recovery from profound neuromuscular block was achieved and no adverse events or other safety concerns were reported.

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