Journal
ANESTHESIA AND ANALGESIA
Volume 108, Issue 3, Pages 906-908Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1213/ane.0b013e3181948a6f
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At our institution, high-dose IV dexmedetomidine is used to provide sedation for pediatric patients undergoing nonpainful radiological imaging studies. Some of these patients exhibit marked bradycardia (more than 20% deviation from the lowest age-adjusted normal values) while maintaining an arterial blood pressure within an acceptable normal range. We report on three cases wherein treatment of dexmedetomidine-induced bradycardia with IV glycopyrrolate (5.0 mu g/kg) not only resulting in resolution of bradycardia but also resulting in an exaggerated increase of arterial blood pressure.
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