Journal
INTERNATIONAL JOURNAL OF NANOMEDICINE
Volume 10, Issue -, Pages 6371-6394Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJN.S86033
Keywords
nanotechnology; nanointerfaces; biofilm-related oral diseases; tissue engineering; drug delivery; toxicity
Funding
- Priority Research Center Program through the National Research Foundation [2009-0093829]
- Ministry of Education, Science and Technology, South Korea
- UK ESPRC [EP/L026287/1]
- Priority Research Center Program through the Commercializations Promotion Agency for R&D Outcomes (COMPA) - Ministry of Education, Science and Technology, South Korea
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Nanotechnology has rapidly expanded into all areas of science; it offers significant alternative ways to solve scientific and medical questions and problems. In dentistry, nanotechnology has been exploited in the development of restorative materials with some significant success. This review discusses nanointerfaces that could compromise the longevity of dental restorations, and how nanotechnolgy has been employed to modify them for providing long-term successful restorations. It also focuses on some challenging areas in dentistry, eg, oral biofilm and cancers, and how nanotechnology overcomes these challenges. The recent advances in nanodentistry and innovations in oral health-related diagnostic, preventive, and therapeutic methods required to maintain and obtain perfect oral health, have been discussed. The recent advances in nanotechnology could hold promise in bringing a paradigm shift in dental field. Although there are numerous complex therapies being developed to treat many diseases, their clinical use requires careful consideration of the expense of synthesis and implementation.
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