Journal
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 8, Issue 5, Pages 345-354Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2164
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Despite the large evolutionary distance between the plant and animal kingdoms, stem cells in both reside in specialized cellular contexts called stem-cell niches. Although stem-cell-specification factors have been recruited from plant-specific gene families, maintenance factors that repress stem-cell differentiation are conserved between plants and animals. Recent evidence indicates that stem cells in multicellular organisms can be specified by kingdom-specific patterning mechanisms that connect to a related core of epigenetic stem-cell factors.
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