Journal
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION
Volume 24, Issue 5, Pages 1327-1336Publisher
OPTICAL SOC AMER
DOI: 10.1364/JOSAA.24.001327
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- NIBIB NIH HHS [R21EB003111] Funding Source: Medline
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We have developed a compact, multimodal instrument for simultaneous acquisition of en. face quasi-confocal fundus images and adaptive-optics (AO) spectral-domain optical coherence tomography (SDOCT) cross-sectional images. The optical system including all AO and SDOCT components occupies a 60 x 60 cm breadboard that can be readily transported for clinical applications. The AO component combines a Hartmann-Shack wavefront sensor and a microelectromechanical systems-based deformable mirror to sense and correct ocular aperrations at 15 Hz with a maximum stroke of 4 mu m. A broadband superluminescent diode source provides 4 mu m depth resolution for SDOCT imaging. In human volunteer testing, we observed up to an 8 dB increase in OCT signal and a corresponding lateral resolution of < 10 mu m as a result of AO correction. (c) 2007 Optical Society of America.
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