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Adipose-derived stem cells for regenerative medicine

Journal

CIRCULATION RESEARCH
Volume 100, Issue 9, Pages 1249-1260

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/01.RES.0000265074.83288.09

Keywords

adipose tissue; adult stem cells; bone marrow stromal cell; differentiation; tissue engineering

Funding

  1. NCRR NIH HHS [P51 RR000164, RR00164] Funding Source: Medline
  2. NIDDK NIH HHS [P30 DK072476] Funding Source: Medline

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The emerging field of regenerative medicine will require a reliable source of stem cells in addition to biomaterial scaffolds and cytokine growth factors. Adipose tissue represents an abundant and accessible source of adult stem cells with the ability to differentiate along multiple lineage pathways. The isolation, characterization, and preclinical and clinical application of adipose-derived stem cells (ASCs) are reviewed in this article.

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