Journal
OPTICS EXPRESS
Volume 15, Issue 10, Pages 6167-6176Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.15.006167
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This paper describes a new method for carrying out flow cytometry, which employs optical gradient forces to guide and focus particles in the fluid flow. An elliptically shaped Gaussian beam was focused at the center of a microchannel to exert radiation pressure on suspended nanoparticles that are passing through the channel, such that these particles are guided to the center of the channel for efficient detection and sorting. To verify the efficiency of this optical-gradient-flow-focusing method, we present numerical simulations of the trajectories of the nanoparticles in both electroosmotic flow (EOF) and pressure-driven flow (PDF). (C) 2007 Optical Society of America.
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