Copper-catalyzed synthesis of aryl azides and 1-aryl-1,2,3-triazoles from boronic acids

A catalytic method was developed to synthesize aryl and vinyl azides from the corresponding borome acids under mild and operationally simple conditions. In addition, a new one-pot procedure was developed to synthesize 1-aryl- and 1-vinyl-1,2,3-triazoles directly from boronic acids and alkynes, which avoided the need to isolate unstable azide intermediates. (C) 2007 Elsevier Ltd. All rights reserved.