Journal
JOURNAL OF NEUROSCIENCE METHODS
Volume 162, Issue 1-2, Pages 303-308Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jneumeth.2007.01.019
Keywords
electrocorticography; ECoG; electrode localization; X-ray; Talairach coordinates; imaging; standardization
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Funding
- NINDS NIH HHS [NS 41272, R01 NS 497293] Funding Source: Medline
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Medically refractory epilepsy accounts for more than 30% of the epilepsy population. Scalp EEG electrodes have limited ability to localize seizure onset from deep structures and implantation of subdural electrodes with long term monitoring provides additional information. Apart from clinical application, this patient population provides a unique opportunity for acquiring electrocorticography data in research paradigms. We present a method for rapid localization of electrodes using lateral and anterior-posterior X-rays. Skull landmarks and proportions are used for co-registration with the standardized Talairach coordinate system. This MATLAB-based Location on Cortex (LOC) package facilitates rapid visualization of clinical and experimental data in a user-friendly manner. (C) 2007 Elsevier B.V. All rights reserved.
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