4.4 Article

Direct oxidative conversion of aldehydes to nitriles using IBX in aqueous ammonia

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 21, Pages 3651-3653

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.03.137

Keywords

IBX; oxidation; aldehyde; nitrile; ammonia water

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A mild, simple, chemoselective and high yielding procedure for the direct oxidative conversion of aldehydes to nitriles has been developed using IBX in aqueous ammonia. (c) 2007 Elsevier Ltd. All rights reserved.

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