Journal
ORGANIC LETTERS
Volume 9, Issue 11, Pages 2167-2170Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol070658i
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- NIGMS NIH HHS [R01 GM084906] Funding Source: Medline
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Pt(II)-catalyzed cycloisomerization of aziridinyl propargylic esters affords 1,2-dihydropyridines with regiodefined installation of substituents. A mild conversion of the 1,2-dihydropyridines to the corresponding substituted pyridines as well as chirality retention from the aziridinyl propargylic ester substrates have been demonstrated.
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