4.4 Article

Bakers' yeast catalyzed synthesis of polyhydroquinoline derivatives via an unsymmetrical Hantzsch reaction

Journal

TETRAHEDRON LETTERS
Volume 48, Issue 22, Pages 3887-3890

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.03.130

Keywords

Bakers' yeast; Hantzsch reaction; polyhydroquinoline; multi-component reaction

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Bakers' yeast efficiently catalyzes the unsymmetrical Hantzsch reaction through a four-component coupling of aldehydes, beta-ketoesters, dimedone and ammonium acetate to form polyhydroquinoline derivatives in good to excellent yields. (C) 2007 Elsevier Ltd. All rights reserved.

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