Journal
FEBS LETTERS
Volume 581, Issue 13, Pages 2455-2459Publisher
WILEY
DOI: 10.1016/j.febslet.2007.04.051
Keywords
mRNA turnover; decapping; DCP1; DCP2; processing body; arabidopsis thaliana
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Although decapping is an important process in eukaryotic mRNA turnover, little is known about this process in plants. Here, we identified Arabidopsis thaliana decapping proteins AtDCP1 and AtDCP2 and showed that (I) AtDCP2 is an active decapping enzyme, (II) AtDCP1 interacts with itself, (III) AtDCP1 and AtDCP2 are localized to cytoplasmic foci (putative Arabidopsis processing body), and (IV) AtDCP1 and AtDCP2 are essential for post-embryonic development. Our findings provide new insights into the role of decapping-dependent mRNA turnover. (c) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
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