Journal
AIDS
Volume 21, Issue 9, Pages 1208-1210Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/QAD.0b013e32810c8dce
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The ability of WHO clinical staging to predict CD4 cell counts of 200cells/mu l or less was evaluated among 1221 patients screened for antiretroviral therapy (ART). Sensitivity was 51% and specificity was 88%. The positive predictive value was 64% and the negative predictive value was 81%. Clinical criteria missed half the patients with CD4 cell counts of 200 cells/mu l or less, highlighting the importance of CD4 cell measurements for the scale-up of ART provision in resource-limited settings.
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