Journal
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
Volume 143, Issue 6, Pages 730-732Publisher
SPRINGER
DOI: 10.1007/s10517-007-0226-4
Keywords
mice; Lewis lung adenocarcinoma; fucoidan; cyclophosphamide; cathepsins B, L, and D
Categories
Ask authors/readers for more resources
Antitumor and antimetastatic activities of fucoidan, a sulfated polysaccharide isolated from Fucus evanescens (brown alga in Okhotsk sea), was studied in C57B1/6 mice with transplanted Lewis lung adenocarcinoma. Fucoidan after single and repeated administration in a dose of 10 mg/kg produced moderate antitumor and antimetastatic effects and potentiated the antimetastatic, but not antitumor activities of cyclophosphamide. Fucoidan in a dose of 25 mg/kg potentiated the toxic effect of cyclophosphamide.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available