Journal
MONATSHEFTE FUR CHEMIE
Volume 138, Issue 6, Pages 595-597Publisher
SPRINGER WIEN
DOI: 10.1007/s00706-007-0658-6
Keywords
indole; heterocycle; solvent; free; aldehyde
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Bis(indolyl)methanes were synthesized by the reaction of indole derivatives and aromatic and aliphatic aldehydes in the presence of diammonium hydrogen phosphate as a solid catalyst under solvent-free conditions. This methodology offers significant improvements for the synthesis of bis(indolyl)methanes with regard to the yield of products, simplicity in operation, and green aspects by avoiding toxic catalysts and solvents.
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