4.5 Article

Serologic evidence for regional differences in pediatric cryptococcal infection

Journal

PEDIATRIC INFECTIOUS DISEASE JOURNAL
Volume 26, Issue 6, Pages 549-551

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/INF.0b013e318047e073

Keywords

Cryptococcus neoformans; pneumonia; serology

Funding

  1. NHLBI NIH HHS [HL59842-07] Funding Source: Medline
  2. NIAID NIH HHS [AI33142-02, AI 3774-11] Funding Source: Medline
  3. NIGMS NIH HHS [GM07142-01] Funding Source: Medline

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Cryptococcus neoformans is present in areas contaminated with pigeon droppings. Unrecognized infections are hypothesized to occur commonly among immunocompetent individuals. We used serology to estimate prevalence of cryptococcal infection in immunocompetent children from 3 regions. Our results indicate unrecognized cryptococcal infections are extremely common in Bronx children, but uncommon in children from Dutchess County, NY and the Philippines.

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