Journal
INTERNATIONAL JOURNAL OF OBESITY
Volume 31, Issue 6, Pages 942-949Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.ijo.0803532
Keywords
fat; emulsion; weight maintenance; body composition; resting energy expenditure; satiety
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Objective: To assess weight maintenance after weight loss by consumption of yoghurt with a novel fat emulsion (Olibra) including effects on body composition, resting energy expenditure (REE), fat oxidation, hunger feelings and satiety hormones. Design: A randomized, placebo-controlled, double-blind, parallel design. A 6-week weight loss period (2.1 MJ/day) was followed by 18 weeks weight maintenance with test (Olibra) or placebo yoghurt. Subjects: Fifty overweight women (age: 18-58 years, body mass index (BMI) 25-32 kg/m(2)). Measurements: In weeks 1, 7 and 25, a satiety test with questionnaires and blood samples for analysis of satiety hormones. In weeks 2, 8 and 26, REE, body weight and body composition. Results: During weight maintenance after significant body weight reduction, there was no significant increase in body weight in the test group (1.1 +/- 3.4 kg); the placebo group did gain weight (3.0 +/- 3.1 kg, P < 0.001). Compared to the placebo group, the test group was less hungry 4 h after yoghurt consumption in week 25 ( P < 0.05) and showed increased glucagon like peptide-1 values 180 min after yoghurt consumption ( week 25 vs week 1, P < 0.05). Measured REE as a function of fat- free mass (FFM) was significantly higher than predicted REE (P < 0.05) in week 26 for the test group, but not for the placebo group. Fat mass (FM) was significantly more decreased in the test group (6.5 +/- 4.1 kg) compared to the placebo group (4.1 +/- 3.6 kg) ( week 26 vs week 2, P < 0.05). Conclusion: Consumption of Olibra yoghurt improved weight maintenance compared to placebo, which can be explained by the relatively higher REE as a function of FFM, relatively higher decrease in FM and the relatively lower increase in hunger.
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