Journal
ELECTROPHORESIS
Volume 28, Issue 11, Pages 1668-1673Publisher
WILEY
DOI: 10.1002/elps.200600566
Keywords
acrylate monolith; electrochromatography; PDMS microchip
Ask authors/readers for more resources
This paper shows the in situ synthesis of an hexyl acrylate monolith in PDMS microfluidic devices and its subsequent use as stationary phase for electrochromatography on chip. To overcome the ability of PDMS material to absorb organic monomers, surface modification of the enclosed channels was realized by UV-mediated graft polymerization. This grafting procedure is based on the preliminary adsorption of a photoinitiator onto the PDMS surface and polymerization of charged monomers. Next, hexyl acrylate monoliths were cast in situ using photopolymerization process. The chromatographic behavior of the monolithic column was confirmed by the successful separation of derivatized catecholamines in the PDMS device using a 30 mm effective separation length (100 mu m x 100 mu m section). Efficiencies reached up to 200 000 plates per meter.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available