Journal
BIOTECHNOLOGY AND BIOENGINEERING
Volume 97, Issue 2, Pages 207-213Publisher
WILEY
DOI: 10.1002/bit.21411
Keywords
protein structure prediction; protein folding; computational methods
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This review presents the advances in protein structure prediction from the computational methods perspective. The approaches are classified into four major categories: comparative modeling, fold recognition, first principles methods that employ database information, and first principles methods without database information. Important advances along with current limitations and challenges are presented.
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