Journal
LETTERS IN DRUG DESIGN & DISCOVERY
Volume 4, Issue 4, Pages 297-304Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157018007784620040
Keywords
liposomes; meropenem; gentamicin; ciprofloxacin; bacteria
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The antimicrobial activity of two cationic liposomes containing three antibiotics were tested in vitro. Ciprofloxacin loaded in liposomes exhibited a 2-4 times higher antimicrobial activity compared with the free drug. The bacterial sensitivity to liposomal meropenem were similar as to free antibiotic. The least effective were the liposomes containing gentamicin.
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