Journal
JOURNAL OF ENDODONTICS
Volume 33, Issue 6, Pages 643-651Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.joen.2007.01.001
Keywords
caries; dental pulp; innate
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Various cells and inflammatory mediators are involved in the initial pulpal responses to caries. This review focuses on the cellular, neuronal, and vascular components of pulpal innate responses to caries. Discussion will include dentinal fluid, odontoblasts, neuropepticles, and neurogenic inflammation, which are not classic immune components but actively participate in the inflammatory response as the caries progress pulpally. Summaries of innate immune cells as well as their cytokines and chemokines in healthy and reversible pulpitis tissues are presented.
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