Journal
NATURE REVIEWS NEUROSCIENCE
Volume 8, Issue 6, Pages 466-479Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn2137
Keywords
-
Categories
Funding
- Medical Research Council [MC_U117537087] Funding Source: researchfish
- MRC [MC_U117537087] Funding Source: UKRI
- Medical Research Council [MC_U117537087] Funding Source: Medline
Ask authors/readers for more resources
The enteric nervous system (ENS) has been explored by developmental neurobiologists and medical researchers for decades. Whereas developmental biologists have been unravelling the molecular mechanisms underlying the migration, proliferation and differentiation of the neural crest derivatives that give rise to the ENS, human geneticists have been uncovering the genetic basis for diseases of the ENS, notably Hirschsprung's disease. Here we discuss the exciting recent advances, including novel transgenic and genetic tools, a broadening range of model organisms, and the pursuit of ENS stem cells as a therapeutic tool, that are bringing these fields closer together.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available