Journal
JOURNAL OF GASTROENTEROLOGY
Volume 42, Issue 6, Pages 497-500Publisher
SPRINGER TOKYO
DOI: 10.1007/s00535-007-2056-6
Keywords
neuroendocrine tumor; endocrine pancreatic tumor; gastrointestinal carcinoid; nationwide survey
Categories
Ask authors/readers for more resources
Background. We conducted a nationwide survey to estimate the incidence of neuroendocrine gastrointestinal tumors (NETS) newly diagnosed in Japan from 2002 through 2004. Methods. Data on 1541 patients, 514 pancreatic endocrine tumors (PETs) and 1027 gastrointestinal carcinoids (GICs), were collected and analyzed. Results. Nonfunctioning tumors (NF-PET) constituted 47.7% of PETS. Next in frequency were insulinoma (31.7%) and gastrinoma (8.6%). Malignancy was frequent in NF-PETs (46.1%) and gastrinomas (45.5%), but only 7.4% of insulinomas were malignant. The incidence of multiple endocrine neoplasia type-1 associated with PETS was 7.4%. The incidence of GICs was 28.8%, 5.2%, and 66.0% in foregut, midgut, and hindgut, respectively. Carcinoid syndrome and metastases were observed in only 1.7% and 5.6% of GICs, respectively. Conclusions. The incidence of NETs in Japan was clarified by this preliminary study. Comparatively large differences in GICs between Japan and Western nations were present with regard to the location, symptomatic status, and prevalence of malignancy.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available