Journal
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
Volume 79, Issue 2, Pages 215-222Publisher
ACAD BRASILEIRA DE CIENCIAS
DOI: 10.1590/S0001-37652007000200004
Keywords
polymethoxyflavones; antifungal activity; Citrus aurantifolia
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A mixture of the two new flavonols 8-hydroxy-3,4',5,6,7-pentamethoxyflavone (1) and 8-hydroxy-3,3',4' 5,6,7-hexamethoxyflavone (2) was isolated from a commercial sample of Citrus aurantifolia. An array of one- ((HNMR)-H-1, {H-1}-C-13 NMR, and APT-C-13 NMR) and two-dimensional NMR techniques (COSY, NOESY, HMQC and HMBC) was used to achieve the structural elucidation and the complete H-1 and C-13 chemical shift assignments of these natural compounds. In addition, the antifungal activity of these compounds against phytopathogenic and human pathogenic fungi was investigated.
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