Journal
ANIMAL GENETICS
Volume 38, Issue 3, Pages 308-310Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1365-2052.2007.01584.x
Keywords
candidate gene; cattle; single nucleotide polymorphism
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The bovine oxidized LDL receptor 1 (OLR1) was chosen as a candidate gene for association tests with milk composition traits. Genotyping of 773 Italian Brown Swiss for a SNP at position 8232 in OLR1 (NW_215807:g.8232C > A) revealed a frequency of 0.95 for the g.8232C allele. The University of Wisconsin Holstein resource population was genotyped for the OLR1 NW_215807:g.[7160C > T; 7161A > G; 8232C > A] SNPs, and four haplotypes were inferred based on the genotypes of sires and their daughters. Oxidized LDL receptor 1 haplotypes were significantly associated with fat percentage (P = 0.0015). Haplotype [C; A; C] was associated with a significant increase in fat percentage when compared with the other haplotypes.
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